Roscovitine was injected directly (30?min) before shot of A. that single injection of A oligomers induces long-lasting activation of microglia and astrocytes in the hippocampus. We observed also profound, early inflammatory response in the mice hippocampus, leading to the significant elevation of pro-inflammatory cytokines expression (e.g. TNF-, IL-1, IL-6). Moreover, A oligomers elevated the formation … Continue reading Roscovitine was injected directly (30?min) before shot of A